{"id":1654,"date":"2022-01-19T09:01:59","date_gmt":"2022-01-19T09:01:59","guid":{"rendered":"https:\/\/innotub.eu\/nous-etudions-la-tuberculose-des-campagnols\/"},"modified":"2022-01-19T09:20:35","modified_gmt":"2022-01-19T09:20:35","slug":"nous-etudions-la-tuberculose-des-campagnols","status":"publish","type":"post","link":"https:\/\/innotub.eu\/fr\/nous-etudions-la-tuberculose-des-campagnols\/","title":{"rendered":"Nous \u00e9tudions la tuberculose des campagnols"},"content":{"rendered":"\n

Certains rongeurs sauvages, tels que les campagnols, peuvent provoquer la tuberculose, principalement caus\u00e9e par la bact\u00e9rie Mycobacterium microt<\/em>i, et peuvent \u00e9ventuellement propager l'infection \u00e0 d'autres esp\u00e8ces de mammif\u00e8res, sauvages et domestiques. L'un des objectifs du r\u00e9seau Innotub<\/a> est d'\u00e9tudier le r\u00f4le que peuvent jouer les rongeurs dans l'\u00e9pid\u00e9miologie de la tuberculose et, pour cette raison, une infection exp\u00e9rimentale a \u00e9t\u00e9 envisag\u00e9e chez des animaux de laboratoire, plus pr\u00e9cis\u00e9ment chez la campagnol des bois (Myodes glareolus<\/em>), avec la souche pyr\u00e9n\u00e9enne de M. microt<\/em>i (isol\u00e9e dans le sud de la France).<\/p><\/p>\n\n

Cette \u00e9tude, financ\u00e9e par le programme Interreg-POCTEFA (EFA357\/19\/INNOTUB) et le FEDER, a \u00e9t\u00e9 r\u00e9alis\u00e9e dans les installations de l'IRTA-CReSA<\/a>\u00a0 en collaboration avec\u00a0l'Anses<\/a> et avec des animaux des laboratoires install\u00e9s \u00e0 l'Istituto Superiore di Sanit\u00e0<\/em> (Rome , Italie). L'\u00e9tude, r\u00e9cemment publi\u00e9e dans la revue scientifique Microorganisms<\/em><\/a>, a \u00e9t\u00e9 utilis\u00e9e pour d\u00e9crire la pathologie induite par M. microti<\/em> chez les grains de beaut\u00e9 infect\u00e9s par deux voies diff\u00e9rentes (intragastrique et intrap\u00e9riton\u00e9ale) et \u00e0 diff\u00e9rentes doses. La progression de l'infection \u00e0 diff\u00e9rents stades apr\u00e8s la provocation exp\u00e9rimentale a \u00e9galement \u00e9t\u00e9 caract\u00e9ris\u00e9e. Enfin, des signes de transmission ont \u00e9t\u00e9 identifi\u00e9s entre des animaux infect\u00e9s exp\u00e9rimentalement et des animaux t\u00e9moins non infect\u00e9s en contact avec ceux-ci.<\/p><\/p>\n\n

Les r\u00e9sultats confirment la sensibilit\u00e9 des campagnols \u00e0 l'infection par M. microti, indiquent une tendance de l'infection \u00e0 progresser vers une g\u00e9n\u00e9ralisation de celle-ci, et sugg\u00e8rent la capacit\u00e9 des campagnols \u00e0 maintenir l'infection dans leur population et \u00e0 la transmettre \u00e0 d'autres esp\u00e8ces, soit directement ou indirectement.<\/p><\/p>\n","protected":false},"excerpt":{"rendered":"

Certains rongeurs sauvages, tels que les campagnols, peuvent provoquer la tuberculose, principalement...<\/p>\n","protected":false},"author":5,"featured_media":1647,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[59],"tags":[174,128,146],"class_list":["post-1654","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-recherche","tag-campagnols","tag-mycobacterium-microti-fr","tag-tuberculose"],"yoast_head":"\nNous \u00e9tudions la tuberculose des campagnols » Innotub<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/innotub.eu\/fr\/nous-etudions-la-tuberculose-des-campagnols\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nous \u00e9tudions la 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